Undiagnosed Hackathons 2027

Four events on four continents in 2027 — Netherlands, Latin America, USA and Malaysia — each organized by Wilhelm Foundation in collaboration with local partners, with the goal to find new ways to solve the undiagnosed diseases that cannot be solved today.

Friday 11 June 2027 · Erasmus MC, Rotterdam

Meet us at ESHG 2027 in Rotterdam, Netherlands – the Harbour Hackers Edition

European Undiagnosed Hackathon — the Harbour Hackers Edition, 11 June 2027, pre-ESHG 2027 event in Rotterdam: Erasmus MC, Wilhelm Foundation, ECHO, ESHG and ERDERA

On Friday 11 June 2027, the day before the European Society of Human Genetics (ESHG) 2027 conference in Rotterdam, Erasmus MC and Wilhelm Foundation are hosting the European Undiagnosed Hackathon, a full-day event at Erasmus MC, Rotterdam. The event is organized in collaboration with ESHG, ERDERA/ERNs and ECHO.

Multidisciplinary teams of clinicians, laboratory specialists and bioinformaticians will work together to find answers for People Living With Undiagnosed Diseases (PLWUD) who remain without a diagnosis even after exome sequencing. For each family, new whole genome sequencing data will be generated especially for this Undiagnosed Hackathon using state-of-the-art technologies.

Everyone is welcome – all areas and all levels of expertise, from beginner to expert diagnostician. Places are limited, and we aim for a balanced mix of collaborators from across Europe and beyond. Practical details, including registration fees and what to bring, will follow.

Application to take part in the Undiagnosed Hackathon is separate from ESHG 2027 conference registration and will open around the same time.

Details on the ESHG 2027 website Submit a PLWUD

At a glance

When: Friday 11 June 2027 — the day before ESHG 2027 (12–15 June, Rotterdam, Netherlands)
Where: Erasmus MC, Rotterdam, the Netherlands
Hosts: Erasmus MC and Wilhelm Foundation
With: ESHG, ERDERA/ERNs and ECHO
Who: All areas and all levels of expertise — places are limited
Families: PLWUD still without a diagnosis after exome sequencing; new whole genome sequencing data for each family
Apply: Separate from ESHG 2027 registration; opens around the same time

The Undiagnosed Hackathon is a research project. Every potential diagnosis must be validated by the responsible clinician before it can mean anything for a family.

Later in 2027

Latin America, USA and Malaysia

Two children wearing glasses colouring with markers at a table at an Undiagnosed Hackathon

9–11 October 2027

Undiagnosed Hackathon in Porto Alegre, Latin America

The first Wilhelm Foundation Undiagnosed Hackathon Latin America in collaboration with Roberto Giugliani, House of Rares. A Tools Workshop, two days of work on the most complex unsolved cases, and the local families there in person.

Applications for collaborators and for families will open on this website.

Email us for updates →

Collaborators gathered around two laptops at the first Undiagnosed Hackathon workshop at ASHG 2026 in Montréal

October 2027

Meet us at ASHG 2027 in Nashville, USA

An Undiagnosed Hackathon workshop at the American Society of Human Genetics (ASHG) 2027 Annual Meeting, October 2027 in Nashville, Tennessee, USA.

The workshop date and how to take part will be announced here. Want to be the first to know?

Yes – keep me posted →

Collaborators working together on laptops around a table

November 2027

Undiagnosed Hackathon in Kuching, Malaysia

Held during the Asia-Pacific Conference of Human Genetics (APCHG 2027) in Kuching, Sarawak — bringing the Undiagnosed Hackathon back to Southeast Asia after Singapore 2026.

Dates, host institution and applications will be announced here.

Ask to be kept informed →