UNDIAGNOSED HACKATHON 

Mayo Clinic

September 22-24
Rochester, Minnesota
USA  

#undiagnosedhackathon2025

Pioneered by Wilhelm Foundation

Purpose

350 million people live with an undiagnosed disease worldwide. Genome sequencing can provide answers for 40 % of the People Living With Undiagnosed Disease (PLWUD) but around 60% still don't receive a diagnosis.
The purpose of the Undiagnosed Hackathon is trying to find new ways and collaborations to solve the undiagnosed diseases, that can’t be solved today.

In this unique event multidisciplinary teams of clinicians, bioinformaticians/molecular biologists, scientists, developers, AI specialists and brilliant minds will work together to tackle the most difficult diseases.

The event centers around the PLWUD who, despite the best efforts of their doctors and genetics specialists, have remained undiagnosed.
The PLWUD will be nominated by clinicians worldwide.

Data (preliminary)

At the event, participants will get access to detailed clinical information and phenotyping done with Tip2Toe, transcriptome, and genome data for the PLWUD.
The data will include: 

Sequencing data will be pre-processed by the bioinformatics team as well as through partner platforms.

Raw data is available for 3 months after the event for participants and partners interested in performing re-analysis.

Organizers

Mayo Clinic and Wilhelm Foundation

Publication

"Pushing the boundaries of rare disease diagnostics with the help of the first Undiagnosed Hackathon".  Read the full article in Nature Genetics

IN PARTNERSHIP with

Sponsors

Support

Interested in partnering or sponsoring the hackathon?

Please contact 
info@wilhelmfoundation.org